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Scientists identify potential biomarkers associated with positive immunotherapy response

Findings Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment. The researchers found when T cells are activated, they release a protein called CXCL13, which helps attract more B cells and T cells to the tumor site. The B cells then show the T cells specific parts of the tumor, which leads to increased activation of the T cells and their ability to fight...

A new approach for the synthesis of pharmaceutically relevant fluorinated phenanthridines

Phenanthridines are heterocyclic compounds consisting of two six-membered benzene rings fused to a six-membered ring containing nitrogen. They are found in many naturally occurring organic compounds known for their anticancer and antitumor properties. Due...

New Sensor Chip Detects Disease Pathogens with 10x Sensitivity

Texas A&M AgriLife Research scientists and collaborators at Iowa State University have developed a sensor chip that can detect many disease pathogens with 10 times the sensitivity of currently available methods. The chip also...

machine learning models predict ADHD symptoms in youth

Scientists at the University of Michigan have developed machine learning models to predict childhood attention-deficit hyperactivity (ADHD) disorder symptoms from neurocognitive testing and child characteristics. The study is published in the Translational Psychiatry Journal....

infant visual preference for mother’s face predicts emotional resilience

A recent study including 60 infants was published in the Scientific Reports Journal, which investigated the trajectories of infant visual preference for the mother’s face and how these are related to the development of emotional reactivity...

tropical hunter-gatherers’ diets contradict Paleo diet assumptions

In a recent study published in The American Journal of Clinical Nutrition, researchers assessed the dietary variations of tropical hunters and gatherers and the impact of the collection approach on implied macronutrient proportions. Study: Comparing...

Why a Black couple wouldn’t crowdfund to pay off medical debts

When Kristie Fields was undergoing treatment for breast cancer nine years ago, she got some unsolicited advice at the hospital: Share your story on the local news, a nurse told her. Viewers would surely...

gut microbiome, diet, and SARS-CoV-2 infections

In a recent study published in the Clinical Nutrition Journal, researchers determined the association between the gut microbiome and diet with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection outcomes. Study: Association of Gut microbiota...

growing threat of mosquito-borne diseases

In a recent report published on the European Centre for Disease Prevention and Control (ECDC) website, the agency described how cases of all types of mosquito-borne diseases are increasing in Europe. Study: Increasing risk of...

Effectiveness of up-to-date COVID-19 vaccination in preventing SARS-CoV-2 infection among nursing home residents: study reveals 31.2% protection

In a recent Morbidity and Mortality Weekly Report, the United States Centers for Disease Prevention and Control (US-CDC) reported findings of the surveillance of nursing home residents by the National Healthcare Safety Network (NHSN), wherein they surveyed...

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